Emma Thompson | 40

Emma Thompson is an actress known for her films such as Love, Actually, one of the women burdened with PCOS or polycystic ovary syndrome. One of its effects is difficulty in conceiving and infertility. As such, it pained Emma Thompson to lose her first pregnancy and the fact that she can never have children again. However, in 1999, two years after her loss, Thompson announced her pregnancy. She credits IVF for making her motherhood dream possible.

She and her now-husband Greg Wise are over the moon with their baby Gaia, but Thompson wanted to have more. However, her age prevented her from carrying another baby. The famous actress decided to channel her energy elsewhere by participating in charity works. In 2003, Thompson and Wise informally adopted an adult Rwandan orphan named Tindyebwa Agaba, making her a mother for the second time.